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Duration of receptor binding is expressed as the dissociation constant (koff) of the receptor-ligand complex, measured using a competitive radioligand assay.
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The binding affinity (the apparent 50% inhibitory concentration (IC50)) of [natGa]Ga-CP04 and [natLu]Lu-CP04 complexes for CCK2 receptor was determined in A431-CCK2R celineine using [90Y]Y-CP04 [90Y]Y-CP04itive rasioligand acompetitive the method used by radioligandet according
We first used a competitive binding assay.
Statistical tests conducted use a competitive null hypothesis.
Inhibition of human IgG binding to GAD65 by rFab was tested in a competitive radioligand-binding assay[34].
Assembled complexes can be used in high-throughput DNA strand transfer assays if radio labeled target DNA is employed or in integrase binding assays using a suitable radioligand.
The aim of this study was to achieve the radiolabeling of a new radioligand, to assess its efficacy using a published CCK radioligand 111In-DTPA-CCK8 111In-DTPA-CCK8 111In-DTPA-CCK8asgeting.
The bioaffinity was assessed using a radioligand binding assay employing the recently described small molecule radioligand [H]-VUF11211 [ 31].
HEK cells stably transfected with WT CXCR4 or ΔT were used in a standard competitive radioligand binding assay.
We have investigated the binding of soluble tenascin-C (TN-C) to several cell lines using a radioligand binding assay.
GAD65Ab positivity was confirmed using a radioligand binding assay (RBA) (described below).
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