This study uses a comparative effectiveness design to assess the relative benefits of TM to those obtained from a gold-standard cognitive behavioral therapy for posttraumatic stress disorder (PTSD) in a Veteran population.
They also called for the creation of a "comparative effectiveness institute" that could use the network to "collect and understand the best practices of the country's best providers of care".
Nordo, AH, Eisenstein, EL, Hawley, J, Vadakkeveedu, S, Pressley, M, Pennock, J, and Sanderson, I. "A comparative effectiveness study of eSource used for data capture for a clinical research registry". International Journal of Medical Informatics 103 (July 2017): 89-94.
Normally the national health technology assessment agencies assess comparative effectiveness, because marketing authorisations are not accompanied by a comparative effectiveness study.
Rather, use a comparative note.
Additional gaps in knowledge that could be addressed using such comparative effectiveness research methods include 1) the relative safety of various classes of diabetes-related medications, 2) the safety of particular medications in the same class, and 3) identification of optimal targets for A1C, blood pressure, or lipid control in subgroups of patients with diabetes.
In both the United States and Europe there has been an increased interest in using comparative effectiveness research of interventions to inform health policy decisions.
45 Further, when linked to the DNRP for inhospital treatment data and/or to the Danish Prescription Registry for redeemed prescriptions, a genetic cohort can potentially be used in comparative effectiveness research to provide evidence on the effectiveness, benefits, and harms of different treatments.
A network meta-analysis is the simultaneous comparison of multiple competing treatments in a single statistical model and is increasingly used in comparative effectiveness research.
Consequently, the cost-effectiveness of the screening program, if it were to be measured using real-world, comparative effectiveness program data, may be different.
