Sentence examples for using a coculture model from inspiring English sources

We have previously investigated signal transduction pathways involved in the pathogenicity of P. falciparum malaria by using a coculture model, and identified parasite factors linked to endothelial cell apoptosis termed Plasmodium apoptosis-linked pathogenicitty factors (PALPF) [27].

Using a coculture model of colorectal cancer cell/lymphocyte interactions, we were also able to demonstrate lymphocyte apoptosis induced by tumour cells, with concomitant caspase-3 activity.

In this paper, we conducted experimental studies using a coculture model to gain a better understanding of the interactions between two cell types, leiomyoma cells and extracellular matrix fibrobasts, which are the major components of fibroids.

To investigate the involvement of B cells in dermal fibrosis, we used a coculture model of human dermal fibroblasts (HDFs) isolated from healthy controls or SSc patients with blood B cells and assessed collagen and profibrotic cytokine and markers expression.

In this regard, a modification of the model described by Alfaro-Moreno et al., using a coculture where the endothelial cells and epithelial cells are seeded on both sides of a membrane, demonstrated that by exposing the epithelial cells, an activation of the endothelial cells was evident within 24 h of exposure [ 204].

Pseudoemperipolesis was evaluated using a coculture of RA FLSs and T or B cells.

Apoptosis of K562 cells was induced using a coculture system with SiSo, MCF-7, MCF-7/ADAM9, and L cells.

Using a xenogenic coculture model of human MSCs and bovine chondrocytes, Wu et al. showed that the beneficial effects of the coculture are largely due to increased chondrocyte proliferation and matrix formation induced by MSCs [ 15].

The effect of LY2109761 has been evaluated on soft agar growth, migration, invasion using a fibroblast coculture model, and detachment-induced apoptosis (anoikis) by Annexin V flow cytometric analysis.

Using a cell coculture model, X. Liu et al. characterized the paracrine regulation of steroidogenesis in theca cells by granulosa cells derived from mouse preantral follicles.

Our research establishes the usefulness of a coculture model to study the interaction of paracrine factors between tumor cells and the 'host' cells of the bone microenvironment.