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Then, the approach and models were validated using a clinical trial data set.
The roles and limitations of pilot studies are described here using a clinical trial as an example.
A population pharmacokinetic substudy design of a new chemical entity was evaluated based on the bias in parameter estimates and the power of detecting a specific subpopulation showing different clearance using a clinical trial simulation approach.
We considered using a clinical trial design with cluster randomisation at the level of GP practice.
Models were initially developed using available published data and subsequently refined by top-down approach using a clinical trial.
Using a clinical trial database of hospitalised patients, aged 80 years and above, the most relevant factors for identifying those at risk of an adverse outcome were identified.
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The registered records of all clinical trials in children that were recruiting on 22 May 2009 were identified on the International Clinical Trials Registry Platform using a Clinical Trials in Children search filter.
Embi et al. developed and used a Clinical Trial Alert System which increased the physicians participation and patient enrolment significantly [ 28, 32].
Chimeric antibody-based receptor (CAR) directed against CAIX, currently used in a clinical trial to treat RCC patients, was used as a model receptor.
Such data allow us to consider how the SDI may be used as a clinical trial endpoint.
[C8.] A federal judge has denied a request by two people with Parkinson's disease that he order Amgen to continue giving them a drug they used in a clinical trial that the company discontinued.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com