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The optimum composition was then assessed by using a central composite design (CCD).
Buffer composition and voltage were optimised using a central composite design.
The method was optimised using a central composite design.
The method was optimized using a central composite design (CCD).
This study was carried out using a central composite design.
Experimental conditions were optimized using a central composite design (CCD).
The variables were studied using a central composite design.
The extraction conditions were optimized using a central composite design.
The effective parameters were optimized using a central composite design.
The actual values of the three independent variables were optimized using a central composite design.
The thermal immobilization of PMTDS on zirconized silica was optimized using a central composite design.
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