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Using a cell microarray chip for evaluation of the efficacy of antimalarial drugs, more sensitive and high throughput evaluation is anticipated.
Furthermore, single cell observation can be performed using a cell microarray chip as opposed to population average studies on flow cytometry analysis.
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A cell microarray chip was used to detect for malaria-infected erythrocytes.
In addition, a study investigated the effect of Icariin on the genome expression of BMSCs by using stem cell microarray [ 26].
Tie et al. analyzed the global miRNA expression profile in highly invasive and low-invasive gastric cancer cells using a miRNA microarray and found that miR-339-5p wasignificantlyly downregulated in highly invasive gastric cancer cells [ 25].
To explore the potential mechanisms by which 1,25(OH)2D3 enhances the susceptibility of Kasumi-1 and MDA-MB-231 cells to NK92 cells, we screened the miRNAs that were modulated by 1,25(OH)2D3 in Kasumi-1 cells using a miRNA microarray.
We then analyzed gene expression profiles in the treated cells using a cDNA microarray consisting of 18,432 genes.
This study analysed the different gene expression of OGE and ERM cells using a DNA microarray technique.
Ray and Enquist have compared the cellular pathways regulated by PrV and HSV-1 during infection of rat embryonic fibroblast cells using a rat microarray [ 12].
For example, gene expression profiling of metastatic cells using a cDNA microarray approach has identified genes responsible for metastasis [ 27, 37– 37].
We further analyzed the effects of HBx mutants on the expression pattern of the transfected Huh7 cells using a cDNA microarray assay (as shown in supplementary material 2 available at Carcinogenesis Online).
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