Using a candidate gene approach allows us to identify such genes with potential relevance in prediction.
Previous studies using a candidate gene approach, family linkage studies, and gene expression profiling uncovered a number of type 2 genes, but the genetic basis of common type 2 diabetes remained unknown.
We attempted to identify possible L. pneumophila enzymes responsible for the rRNA cleavage by using a candidate gene approach.
We attempted to identify the L. pneumophila protein responsible for the rRNA cleavage using a candidate gene approach.
There have been a number of genetic association studies for persistent S. aureus colonization using a candidate gene approach.
Using a candidate gene approach, six of the ten markers we used gave evidence of an association between reactor status and either genotype or heterozygosity.
Here, using a candidate gene approach, we sought to determine whether genetic variation at the NPSR1 locus influences individual predisposition to rheumatoid arthritis.
As such, this study provides a foundation for future studies using a candidate gene approach to investigate neurobehavioral and homeostatic responses to chronic partial sleep deprivation.
The specific clock gene variants studied here were previously identified to be common polymorphisms in clock genes using a candidate gene approach [29](see Methods S1).
Using a candidate gene approach and a case-control genetic association study, we report herein on the association of the MECP2 gene region with SLE in two independent cohorts of SLE patients and controls.
Using a candidate gene approach in a two stage selection process a panel of protective and susceptibility SNPs were identified that individually confer only small effects on risk of lung cancer (OR ranging from 0.3 to 2.6).
