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This significant increase in median survival time using a cancer model that is different from the p53−/− mouse further confirmed the pro-tumorigenic effect of oxygen.
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The induction of USP17 expression in cancers by macrophages was further verified using a cancer animal model for studying the effects of macrophages on tumor growth.
Here, using a cancer pain mouse model we selectively ablated two separate populations of putative nociceptors innervating the cancer microenvironment and observed distinct behavioral changes.
Using a cancer pain mouse model that is produced by injecting SCC supernatant into the hind paw, we previously showed that extracellular secretions from the cancer, not growth of the cancer, directly produced mechanical allodynia [ 22].
This study is the first to use a cancer disease model as the framework to identify hormone responsive genes.
To the best of our knowledge our study is the first to use a cancer disease model as the framework to identify hormone responsive genes.
Furthermore, we have recently demonstrated the anti-cancer effect of exendin-4 using a prostate cancer model [ 19].
Because we used a cancer care model and interviews with health care professionals we think that we have taken practical considerations into account that will improve the intervention implementation.
Recent studies using a murine cancer model showed that Stat3 is also an important molecule in the maintenance and anticancer drug responses of cancer stem-like cells (CSCs).
The current study investigates roles of UEV1A, UEV1C and MMS2 in tumorigenesis using a breast cancer model.
Using an animal cancer model, we observe mice with excess visceral adipose tissue or plasma FFAs due to a high fat diet experience early bodyweight loss, early appearance of high number of CTCs, and increased lung metastasis.
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