Exact(2)
Hence, the loss of information involved when using a binary cut-off for the classification of active and inactive compounds is minimal [39].
For continuous predictors, checks were undertaken for non-linearity and, if found appropriate, re-modelling of such variables was conducted e.g. either using a binary cut-off (e.g. hemoglobin, blood glucose) or by expressing as a linear trend above a certain level (e.g. serum creatinine).
Similar(58)
27 We used a binary cut-off score of >2.
A secondary analysis was undertaken using a binary cut off of 'depressive symptoms', to account for subclinical symptoms of depression.
They used a binary cut off of 25 for the BMI in this study.
One reason to use also a binary cut-off has been that the range of exposures within the highest quartile seemed to be larger than differences between quartiles.
Two principal components, 10-fold cross-validation and a binary cut-off using the 50th percentile were used to generate two prognostic groups.
Two-by-two contingency tables were used to calculate sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for plasma HBP at a binary cut-off.
In a second sensitivity analysis exposure was considered a binary cut-off (90% percentile).
Since data on length of post-operative hospital stay were skewed, a binary cut-off of 7 days was implemented.
In a sensitivity analysis exposure was also considered as a binary cut-off (cut-off 90% percentile) to compare those 10% with the highest exposure to the remaining participants (data not shown).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com