Other experiments were performed using various cell types, with many ENCODE ChIP-Seq datasets generated using five transformed cell lines (i.e., K562, GM12878, HepG2, H1-hESC and HeLa) [47,48].
Cellular cardiomyoplasty for myocardial infarction has been developed using various cell types.
Studies using various cell types have implicated oxidized flavins (riboflavin, FAD, FMN) as the source of much of the signal in this spectral range [9] [12].
In vitro studies using various cell types exposed to a variety of toxic stimuli have reached conflicting conclusions as to whether CysC is protective or toxic to the cells (for review [3]).
Further studies using various cell types or using animals are needed to address this issue.
Additionally, different research groups have evaluated the cytotoxicity of polyaniline in vitro using various cell types such as fibroblast, pheochromocytoma (PC12), and cardiac myoblast (H9c2) cells [ 14, 15].
Using various cell types (HEK293, MEF, EEF, LEFs) under starvation conditions, they reported increased AMPK activity and phosphorylated tuberous sclerosis 2 (TSC2).
Particularly interesting seems that, in both in vitro and in vivo settings, using various cell types, primary neuronal cultures as well as murine brain samples, PSEN deficiency was shown to result in endolysosomal autophagic abnormalities [ 33, 37, 69, 97, 164].
Other studies using various cell types have shown that the regulation of PDCD4 expression can occur at many levels including transcriptional and translational and that these mechanisms could be essential for a coordinated and controlled regulation of the cellular protein levels [ Lankat-Buttgereit and Goke, 2009].
As a parallel approach by characterising the changes in the proteome of differentiating CSM14.1 cells we used various cell type specific antibodies to document the morphological and phenotypical alterations over time.
