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Eight of 10 uses of these agents were during the maintenance period.
Thus, the conjugation of a TLR7 agonist to phospholipid or PEG moieties is a promising strategy to expand the clinical uses of these agents for infectious, malignant, or atopic diseases.
The practical uses of these agents are limited, as streptokinase has antigenic potential exacerbating hypotension, and urokinase in unconcentrated formulations intended for lysis of vascular lines, too low of a concentration in acute PE.
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Children are especially susceptible to these side effects, and this has broad implications across the board, for the use of these agents to treat any disorder".
We haven't taken a stand as a society, and the widespread use of these agents is reflective of our ambivalence".
The problems come when they are used for longer periods of time…Regulatory agencies should reconsider the use of these agents as over-the-counter drugs".
Prolonged use of these agents is associated with tolerance and withdrawal.
"Agricultural pesticides are widely used and there is no effective control of administrative approval, marketing or use of these agents".
Clinicians should be familiar with the therapeutic benefits and limitations associated with the use of these agents in clinical practice.
Use of these agents in metastatic colorectal cancer and potential for use in localized rectal cancer are discussed.
Data regarding the use of these agents in the absence of concomitant intravenous heparin have been conflicting.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com