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Smaug uses guile as well as fire in dealing with his enemies and it is ultimately a very human character flaw — arrogance — that undoes him.
Even the show's more lurid siblings -- "Special Victims Unit" (which deals with sex crimes) and "Criminal Intent" (in which a Columbo-like Vincent D'Onofrio uses guile and brainpower to seduce a villain into self-exposure) -- are not so harrowing that they keep you up at night.
Joule might have been another Jade from Beyond Good & Evil: a whip-smart female protagonist whose likeability stems not from her looks or cool move set, but how she tackles the problems before her and uses guile and ingenuity as effortlessly as she does a firearm.
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In between, Beckett used guile and a lot of curveballs to baffle the Rays.
Stanky was a cunning scrapper, a little borderline guy who used guile and aggression to make up for his deficiencies.
Instead of using Guile directly, we separated much of the user interface code into a package called libctl, in the hope that this might be more generally useful.
Google is using guile to re-create a guileless world, under the assumption that what we don't know should help us.
In his wartime office from hell, Mr. Pemper repeatedly risked his life, using guile to gain access to classified documents and a photographic memory to record them.
Then, in October, he fought Márquez, using guile and speed to get himself a twelve-round victory, by decision, that most agreed he deserved.
George was potentially a better politician than Bute, for he had tenacity, and, as experience matured him, he could use guile to achieve his ends.
libctl automatically handles the communication between the program and Guile, converting complicated data structures and so on, to make it even easier to use Guile to control scientific applications.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com