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SAM uses a permutation method to determine the significance of changes in expression by assimilating a set of gene-specific t-tests and hence reports a false-discovery rate (FDR) rather than a probability.
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We first generate locus-wise permuted P-values for association with the phenotype from multiple maps, which can be done using a permutation method appropriate to each population.
To calculate FDR, we used a permutation method to estimate the false positive number FP.
The choice of the model was determined using a permutation method [ 24].
The significance of any differentiation was tested using a permutation method with 10,000 replications.
The significance (P-values) for the r values was computed using a permutation method described previously (Gardner et al. 2005).
This approach revealed highly connected genes within the JIA interactome by testing the significance of biological networks using a permutation method (10,000 permutations).
Differences in the ST composition of the 2009 and 2011 populations were estimated using the classification index, with significance assessed using a permutation method [ 6, 19].
To establish whether friends exhibited correlated outcomes in the network at a single point in time, we used a permutation method.
Dapple searched for significant physical connectivity among proteins encoded by genes in loci associated with disease according to PPIs reported in the literatures and revealed highly connected genes by testing the significance of biological networks using a permutation method (1000 permutations) (Rossin et al. 2011).
The LA method uses a permutation test for the identification of significant LA gene pair values.
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