Although TPS represents a highly sensitive marker of tumour proliferation in this IAS clinical model of controlled tumour regression and regrowth, its low specificity compared with PSA limits its usefulness to monitoring of prostate cancer patients with proven absence of non-specific elevations of this marker.
Therefore, although our results confirm the usefulness of NIR to monitor oxidase activity in vivo, we suggest appropriate caution about data interpretation.
The tumor marker character of the HCY, namely the elevated HCY levels in cancer patients [ 45- 54], the elevated HCY levels in advanced clinical stages [ 49, 53] and the usefulness of HCY to monitor therapeutic effects [ 48, 49, 54, 55] has also been demonstrated.
These results also demonstrate the simplicity and usefulness of this method to monitor ligation mixtures using PCR.
Objectives: To evaluate the feasibility of an alternate system for the estimation of CD4 and CD8 counts in normal south Indian adults and validate the usefulness of this assay to monitor the counts in HIV seropositive individuals.
Subsequent studies should explore the usefulness of this indicator to monitor the effect of viral infections on disease progression and survival.
Upon induction of autophagy either with sucrose or trehalose treatment, TFEB-Flag translocated to the nuclei, thus confirming the usefulness of AdTFEB-Flag to monitor TFEB dynamics in TM cells.
This validates the use of the CCQ to monitor recovery and indicates the potential usefulness of this tool in monitoring clinical recovery post viral infection, and as an evaluative tool in treatment studies [25].
For T. b. brucei, the usefulness of this triple marker to monitor the entire parasite cycle in both tsetse flies and mice was further demonstrated.
Our results clearly indicate the usefulness of multiple assays systems to monitor both beneficial and toxic effects of drugs with broad range of in vivo activity.
