With the future developments, as discussed below, the power and usefulness of the reference atlas will be growing.
Therefore, a careful validation of the usefulness of potential reference genes is essential.
The usefulness of the reference values reported here, given their wide normal range, will ultimately be determined by the values that are obtained from diseased dogs.
Enhanced by such adjustments we recognise the general usefulness of the reference strategy if population conditions are not as bad as in middle or western continental Europe.
The usefulness of the reference values reported here, given their wide normal range, will ultimately be determined by the values that are obtained from a large numbers of diseased dogs.
Even the attempted justification of the standard of usefulness by reference to the will of tian or Heaven (in chapter 26) has a suspect circularity to it.
This requires re-evaluation of the usefulness of previously used reference genes, but many studies continued to use the above mentioned classical reference genes for normalization without any validation of their suitability in real-time PCR.
Index of individuality (II) was calculated as CVI/CVG whereby a low value (<0.60: high individuality) indicated a low usefulness of population-based reference intervals, whereas a high value (>1.40: low individuality) indicated a high usefulness of population-based reference intervals, particularly when an unusual result was repeated for verification.
The usefulness of a certified reference material (CRM) for analytical method validation and quality control purposes is attributed mainly to its key properties, namely homogeneity and stability.
The usefulness of the serum reference 2-DE map was confirmed by two different comparative investigations.
To test the usefulness of various endogenous reference gene we resorted to the well characterized expression of the melanocytic lineage-specific gene gp100/Pmel17 [ 31] that is expressed exclusively though heterogeneously in cells of melanocytic lineage [ 35, 36].
