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Of these factors, the low and nonselective cellular uptake of antisense oligonucleotides has hindered its therapeutic usefulness most severely.
An empirical evaluation of PESearch, PEControl, and PEReview revealed that novices felt the most important aspect of the tools for downloading and usage intentions was its usefulness; most experts felt the tool met the design principles as specified.
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These encumbrances have limited the usefulness of most methods and prevented their widespread use in population-based biomonitoring programs.
In order to acquire the OPD profiles of the cells and demonstrate the usefulness of most of the parameters defined above, we used IPM to image HeLa cells.
This overlapping of symbolism and usefulness is most evident in the smith's choice of materials.
From the point of finding usefulness, the most valuable information was gained from documentation reviews.
While modern scanners can scan at up to 6400 dpi, those elevated resolutions produce very large files, and do little to enhance the usefulness of most office documents.
The clinical usefulness of most conservative chemotherapeutics is restricted either by the incapability to deliver therapeutic drug concentrations to the target soft tissue or by Spartan and harmful toxic side effects on normal organs and tissues.
Today at Disrupt SF, TechCrunch founder and alum Michael Arrington interviewed venture capitalist Vinod Khosla in a conversation that covered a number of topics including egg substitutes, animal cruelty, city design, Uber, the usefulness of most members of the professional investing community — and one of Khosla's newest interests, machine learning.
Unfortunately, Messick's unitary concept may exclude vital evidence contributing towards this current evaluation, and thus, Bachman and Palmer's (1996) concept of usefulness is most appropriate, because it incorporates additional test qualities within the evaluation framework that will be addressed in this review.
The usefulness was most limited in problems related to cervical spine, unclear cerebral symptoms and abdominal pain.
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