Exact(9)
We have extensively discussed in the past the challenges to the efficient development and validation of useful therapeutics [5 8].
A range of approaches are being developed to generate inhibitors of protein protein interactions that may form useful therapeutics for human disease.
"There have been several attempts to develop defensins as useful therapeutics, but these attempts have fallen just short of their goal," says Charles Bevins, an immunologist at the University of California, Davis.
These data suggest that NO-np may be useful therapeutics for microbial abscesses.
Some of these MAbs could potentially be developed into useful therapeutics in treating the devastating diseases caused by BP and BM [18].
Furthermore, even compounds with no potential to be developed into useful therapeutics are valuable as tools for probing the parasite's biology [ 6].
Similar(51)
Liposomal nanomedicine has led to clinically useful cancer therapeutics like Doxil and DaunoXome.
The inhibitors of factor-inhibiting HIF-1 (FIhavehave been shown to be useful as therapeutics for the treatment of anemia.
The ability to rationally design the site of novel protein protein interactions is an important step towards creating new proteins that are useful as therapeutics or molecular probes.
PC-1 (NPP-1) inhibitors may be useful as therapeutics for the treatment of CDDP (calcium pyrophosphate dehydrate) deposition disease and osteoarthritis.
The inhibitors of phosphatase of regenerating liver-3 (PRL-3) have been shown to be useful as therapeutics for the treatment of cancer.
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