Mouse models of astrocytoma provide a useful system for understanding tumorigenesis of astrocytomas and for designing and testing new therapies.
Our experiments also provide a useful set of ionic binding affinities in a simplified system for testing new affinity prediction methods.
Although tumor angiogenesis in breast cancer is complex, the VEGF/vascular endothelial growth factor receptor (VEGFR) system provides a useful model for testing new angiogenesis inhibitors that target this pathway.
Besides increasing our understanding of the disease mechanisms involved in ichthyotic syndromes, this model system is potentially useful for testing novel treatment modalities, for example by performing a small molecule library screen for compounds that are able to suppress the phenotype.
Cell culture-based systems might be particularly useful for testing how the individual components contribute to complex reprogramming events in the germline, which in turn could improve our ability to control cell fates.
BUT it's a jolly useful platform for testing new international markets.
This model is useful for analyzing mechanisms of remyelination in the adult rodent nervous system and for testing therapeutics to enhance remyelination.
Although perfectly regenerating systems can reveal in great detail how regeneration works, by definition they are less useful for testing therapeutic interventions.
They are also useful for testing drug abusers, he said.
