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Its stubborn persistence is useful proof of the irredeemability of a corrupt system.
Mobi-Link was a functional demo and was a very useful proof of capability and concept, but it wasn't the driver behind our first funding.
At this stage, therefore, clinical trial data provide useful proof of biologic concept but IL-15 should not be considered a validated clinical target.
These represent experimentally-testable hypotheses, and this study as a whole serves as a useful proof of principle for the structural systems pharmacology analysis of antibacterials.
Finally, our data the first profile of genome-wide gene expression levels in a wild primate population—serve as a useful proof of principle of the ability to concurrently generate genome-wide gene expression phenotype and genotype data, and to relate them to each other using eQTL and ASE approaches.
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Though the number of data points is severely limited in the cross-country regressions, these analyses are useful proof-of-concept that the data can be used analytically.
Using pre-treatment before the bacterial challenge is arguably a limitation of our studies in the primary pneumonia model; this approach is useful for proof-of-principle but does not mirror likely clinical usage.
In an MCI stage, a composite that considers cognitive, functional, and global items is likely to give the best chance for optimal measurement of decline, reflects a global approach to the disease and would be particularly useful for proof-of-concept studies.
Although useful for proof of principle studies like presented here, unmodified LPEI is not the ideal carrier for targeting transgene expression to the tumor after systemic injection: In our experiment presented here, the level of luciferase activity in tumors strongly varied between individual animals (CMV driven plasmid: 4 high, 2 low, AFP driven plasmid: 3 high, 3 low).
Advanced MRI modalities offer imaging metrics of tissue integrity and may be useful in the proof-of-concept evaluation of putative neuroprotective therapies.
This work is a useful generalisation and proof-of-concept realisation of an engineering solution to enable RESTful services to be assembled in workflows to analyse general content in a way that is not immediately available elsewhere.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com