To date there are no clinically useful pan-MβL inhibitors available, mainly due to the unawareness of key catalytic features common to all MβL brands.
The AE1/AE3 monoclonal antibody cocktail[ 2, 3], raised against human epidermal keratin, was the most useful pan-epithelial marker.
In mammals CD79α is expressed on very early B cells through to mature B cells [70] making it a useful pan-B cell marker [71 73].
The findings also provide a deeper insight into venom variations due to geography, which is crucial for the development of a useful pan-regional antivenom.
The objective of this study was to examine whether Plexin D1 might be clinically useful as a pan-tumor vessel and pan-tumor cell target in solid tumors.
To examine whether PLXND1 might be clinically useful as a pan-tumor vessel and pan-tumor cell target in solid tumors we analyzed PLXND1 expression in a wide range of human tumors of different origin, various pre-malignant and non-tumor related tissues by immunohistochemistry and mRNA in situ hybridization.
To explore whether PLXND1 may be clinically useful as a pan-tumor endothelium and a pan-tumor cell target we examined the expression profile of this protein in a large variety of human tissue samples.
(The BBC's eschewal of received pronunciation – RP – is inverse snobbery: it was a useful instrument of pan-British comprehensibility. The regional accents that have replaced RP are vocal manifestations of identity politics, of parochial apartheid).
Our results indicate that LFU in combination with colistin plus vancomycin may be useful in treating pan-resistant A. baumannii infections.
The bone is not crucial, but is useful for flavouring the pan juices, so ask the butcher for it.
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