Sentence examples for useful in vitro model from inspiring English sources

To study the regulation of POMC expression by Sirt1, we used the AtT20 cell line that has been shown to be a useful in vitro model for this type of studies [26], [27].

In conclusion, SCRH represent a useful in vitro model to predict the hepatotoxicity of trabectedin observed in vivo.

Thus, this novel 3-D co-culture system provides a useful in vitro model to investigate the functional role and interplay of developing ECMs and BMSCs during cardiomyogenic differentiation.

Thus, this novel co-culture system provides a useful in vitro model to investigate the functional role and effects of neovascularization in the proliferation, differentiation and maturation of BMSC derived osteoblasts.

These effects are similar to human responses to vesicants in vivo and suggest that the full thickness skin equivalent is a useful in vitro model to characterize the biological effects of mustards and to develop potential therapeutics.

Our 2-D co-culture system provides a useful in vitro model to elucidate various molecular mechanisms underpinning the integration and orderly maturation and differentiation of BMSCs into neo-cardiomyocytes during myocardial repair and regeneration.

These tubes resembled venules and "giant" capillaries in both their cellular organization and function, and we believe that they will serve as useful in vitro models of inflammation under constant perfusion.

Thus, in addition to ES cells, these alternative stem cell lines will provide useful in vitro models to examine the lineage-specific regulation of chromatin structure.

Recent studies have been successful in generating disease-specific induced pluripotent stem cells (iPSCs) from a variety of neurodevelopmental and neurodegenerative disorders, providing useful in vitro models.

Identifying useful in vitro models of the effect of stress on neurons in diabetic conditions is important if the mechanisms of diabetic retinal neuropathy or other complications of diabetes are to be explored and perhaps eventually targeted therapeutically.

This finding suggests that these cell line models of breast cancer subtypes closely reflect tumor miRNA expression patterns and are a useful in-vitro breast cancer model for functional analysis of miRNA.