Sentence examples for useful efficacy from inspiring English sources

Therefore, the issue with NPY receptor antagonists, by shutting down endogenous NPY tone, is whether they would provide clinically useful efficacy profiles.

These findings suggest that Day 3 endpoints are useful efficacy endpoints in the design of clinical trials for antimicrobial agents for treatment of cSSTI.

In contrast, SERDs may have useful efficacy following aromatase inhibitors because of their unique mechanism of action, and clinical trials to determine their optimal use or sequence are ongoing.

Although useful, the efficacy of traditional phytoindicators is sometimes hampered by limited distribution and abundance, variable browse susceptibility, and lagged responses.

Therefore, animal models in general are not useful for efficacy validation due to species specificity of gene sequence.

Therefore, the availability of primate R5 SHIV challenge viruses that encode tier 1 as well as tier 2 primary HIV-1 envelopes will be useful for efficacy testing of candidate AIDS vaccines in macaque models.

Although these agents have proven to be useful, their efficacy is reduced by dose-limiting side effects and, in some cases, a constitutive mode of cholinergic manipulation.

DAs are considered particularly useful when efficacy is unclear, outcomes are uncertain, and/or subjective judgments about benefits and risks are required [ 24].

Combining this technique with in vivo Doppler ultrasound measurements in mouse models will be particularly useful for efficacy and safety profiling for maternal treatments of FGR/PE.

The HIVE mouse model has proven to be useful for efficacy studies to screen potential neuroprotective compounds, such as sodium valproate (Dou et al., 2003), for their applicability in the setting of HIV-associated neuroinflammation.

Although useful for efficacy, such trials are usually too small and with too short a follow-up to yield adequate information on rare adverse drug reactions (ADR) and long-term safety [ 11].