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Researchers charged with the task of evaluating such programs are recommended to consider adopting a randomised controlled design, to enable stronger statements about the effect of stepped care approaches and a useful cost effectiveness analysis.
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We assessed cost effectiveness using cost effectiveness acceptability curves.
Quality-adjusted life-years may not fully capture diverse benefits of public health interventions but are useful for benchmarking the cost effectiveness of public health against clinical services.
In addition, it would be a useful exercise to analyze the cost effectiveness of administrative costs in the social sector ministries -- administrative expenses represent major budgetary allocations (both salaries and other operational expenses).
A study with a larger sample size and longer period of follow-up will be useful to determine the clinical and cost effectiveness of CaPE and will help with the planning of efficient and culturally appropriate interventions in Pakistan that could serve as a model for other low-income countries.
A multidimensional network meta-analysis model for survival data is extremely useful for cost-effectiveness analysis because estimates of expected survival differences of competing interventions are less likely to be biased [ 7, 8].
This figure allows for comparisons of survival proportions at different time points (including median survival), as well as comparisons of expected (i.e. mean) survival, which is useful for cost-effectiveness evaluations.
Although MRI has been accepted as the most useful examination method [27], we used ultrasound due to its advantages of cost effectiveness, time efficiency and non-invasive nature.
Cost effectiveness studies would be particularly useful in determining this.
Further information on the cost and cost effectiveness of centralisation would also be useful for policy makers and commissioners.
By integrating pharmacological and pharmacoeconomical models, earlier assessment of expected clinical utility and cost effectiveness can be obtained, which can be useful to estimate cost effectiveness and clinical utility a priori, rather than to only assess these important aspects post hoc.
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