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Specialized parenteral nutrition solutions have been used when adequate enteral intake is not possible.
16 In response to these concerns, the American Society for Bone and Mineral Research stated that food remains the best source of calcium and that supplements should only be used when adequate dietary intake of calcium cannot be achieved.
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Dura mater is generally used when suturing is not an adequate procedure to treat damage to the brain.
In case of refractory cardiogenic shock, veno-arterial extra corporeal membrane oxygenation (VA-ECMO) is used when pharmacological support fails to restore adequate perfusion.
This technique also is used when a needle biopsy does not provide adequate information for a diagnosis to be made.
Quadriceps snip or V-Y lengthening was used only when adequate exposure could not be obtained otherwise.
While the use of preclinical animal models for efficacy assessment will probably also persist, it is less clear that current preclinical animal models are entirely adequate or appropriately used (even when adequate), or that an optimal panel of such models to predict efficacy with sufficient accuracy currently exists.
While biomarkers may be used to accurately predict when adequate levels of nutrients are reached, a personalised approach will account for inter-subject variability in response, pre-emptive timing, e.g. preconception will optimise response and the joint participation of scientists in academia, governments and industry will ensure the best outcome.
Our findings demonstrate that use of an automated bolus advisor can be efficacious and clinically meaningful in MDI therapy, and that most patients are willing and able to use this technology appropriately when adequate clinical support is provided.
When adequate normalisations are used together with relevant dimensionless numbers, the head values obtained from the different ESPs proved to match quite well along curves of constant specific speeds.
It may also be used in desmoplastic melanoma, but only when adequate surgical margins are not obtainable [ 70, 71].
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