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This study showed how a mathematical model can be used to inform sample size considerations for RCTs.
A power analysis is not indicated as an intra-class correlation coefficient will be calculated and used to inform sample size calculations for subsequent large-scale trials.
The difference in body mass index (BMI) z-score between arms was used to inform sample size calculations for a definitive trial.
Analysis was used to inform sample size as we sought to achieve 'saturation', such that new data were not leading to any further population of the themes ('categories') with insight by the end of data collection [ 40].
This pilot study found the study methods to be feasible and has provided previously unavailable data which will be used to inform sample size estimates for the design of a larger definitive trial.
This study investigates how a mathematical model can be used to inform sample size calculations for a randomised controlled trial (RCT) using the example of Chlamydia trachomatis infection and pelvic inflammatory disease (PID).
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A conservative estimate using the 95% upper confidence limit will be used to inform the sample size calculation of the definitive RCT. 3. To enable selection of the most appropriate primary and secondary outcome measures.
Differences between arms on the short version of Conners' Parent and Teacher Rating Scales Revised will be compared and also used to inform the sample size required for a future definitive cluster RCT.
We planned a priori to transition directly from our pilot RCT to a definitive RCT if feasibility was established, with the pilot event rate used to inform the definitive sample size estimation.
Pre-pregnancy BMI and gestational weight gain (around 38th week) data were only available to the researcher towards the end of the participant's 3rd trimester and therefore could not be used to inform the purposive sampling during pregnancy.
A key feature of both proposed algorithms is that the surrogate model evolves continuously with the sample selection and is used to inform the selection of new samples such that it converges rapidly to an accurate representation of the limit surface.
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used to categorize sample
used to determine sample
used to avoid sample
used to describe sample
used to inform policy
used to extrapolate sample
used to generate sample
used to measure sample
used to analyze sample
used to calculate sample
used to enable sample
used to compare sample
used to summarize sample
used to monitor sample
used to derive sample
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