Sentence examples for used to induce differentiation from inspiring English sources

The research to this end is extensive and is dominated by studies relating to classical biochemical signalling molecules used to induce differentiation of ASCs and BMSCs.

In addition, cutting-edge genetic manipulation techniques are used to induce differentiation selectively toward the endodermal lineage (Kobayashi et al. 2015), and might be used to introduce suicide genes under neuron– or germ cell specific promoters to induce apoptosis of unwanted cells after differentiation (Rashid et al. 2014).

The same protocol, with omission of FCS, can also be used to induce differentiation of rMAPC.

Unconditioned medium (UM, standard hESC medium without bFGF) was used to induce differentiation at day 2. Total RNA was extracted from feeder-free ES cells or EBs using RNA extraction kit (Ambion) and was reverse-transcribed.

As we have observed that RASSF9 is transiently induced when 2 mM calcium is used to induce differentiation among keratinocytes, it would be interesting in the future to examine whether RASSF9 binds to endogenous Ras protein targets in keratinocytes under high-calcium treatment, leading to the attenuation of Ras activity during early differentiation in these cells.

This mixture, which is frequently used to induce differentiation, had never been tested for study on polyamine to our knowledge.

The differentiation medium used to induce chondrocyte differentiation of the ATDC5 cells was made by supplementing the maintenance medium with 10 μg/ml of bovine insulin (Sigma Aldrich).

Fibronectin has been implicated in the progression of mesodermal differentiation [15] and is commonly used to induce endothelial differentiation from endothelial progenitors (HUVEC or hESC-derived).

Phorbol-12-myristate-13-acetate (PMA) and 1,25-dihydroxyvitamin D3 (VD3) are stimuli commonly used to induce macrophage differentiation in monocytic cell lines but the extent of differentiation in comparison to primary tissue macrophages is unclear.

The microinjection molding technique has been chosen as an industrially viable process, for the accurate and cost-effective mass production of molded micro-patterns, which influence the osteogenic differentiation of human mesenchymal stem cell, in the absence of growth factors commonly used to induce osteoblast differentiation [30].

To enhance the yield of endothelial cells from hESCs, a newly developed protocol was used to induce the differentiation of hESC-ECs by sequential treatment over 4 days with floating EB formation and 8 days of outgrowth differentiation from EBs in EGM-2 medium, which contains abundant growth factors to improve endothelial cell proliferation (Figure 1A).