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The red curves are obtained in the following manner: Simulations using the true parameters were used to generate sample spikes.
We further conclude that these 10 errant HVI∞M2 molecules were produced between the 3rd and final round of double-stranded duplication in the SM-LATE-PCR assay used to generate sample M2.
When alleles are found at intermediate frequencies, required sample sizes are largely independent of p. The analytic theory used to generate sample sizes was verified by MATLAB simulations.
Although this tutorial is focused on population PK modeling, we have provided R code in Appendix 1 that can be used to generate sample size vs. power comparisons such as that depicted in Figure 1 using an NCA approach.
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An adaptive sampling technique is used to generate samples and update the approximated LSF.
A random number drawn out from a normal distribution over the interval [0,1] is used to generate samples from the inverse cumulative distribution function.
For the proposed hybrid approach, the UD is used to generate sampling points and then the SVM is employed to construct the response surface approximating the original inexplicit LSF.
Since Latin hypercube sampling is more efficient and robust than simple random sampling [29, 30], and correlations between variables can be considered by using the correlation matrix during the pairing process [31], Latin hypercube sampling with the Cholesky decomposition method is used to generate samples according to their correlation.
To assess the bioenergetic status of mitochondria oxidizing palmitate, O2 consumption was measured under the incubation conditions used to generate samples for metabolomics analyses.
In practice, and in spite of the unbiased way used to generate samples, it is possible (even likely) to miss some cross-classifications that are present in the population in the sampling effort.
The taxonomic assignments of the 16S sequences were used to generate sample-taxa count matrices.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com