Sentence examples for used to develop prognostic from inspiring English sources
Gene expression profiles generated by microarray have been used to develop prognostic scores, which when coupled with clinical parameters, have proven useful in predicting aggressive GCs and ultimately, outcome [ 13].
We propose that the identification strategy for protein biomarkers described herein is likely to be applicable to other tumour types, and may serve as a model for performance-based selection of biomarkers that can be used to develop prognostic or predictive tests for other tumours where histological assessment is pivotal to risk stratification and prognostication.
The data from Bristol and Birmingham were used to develop the prognostic models (development sample) and the models were validated on the data from Wolverhampton (validation sample).
The 427 cases included for analysis were used to develop the prognostic models for KM2, WT, GCM3 and AT methods.
Patient risk stratification was dependent on the segmentation method used to develop the prognostic model with up to 73 patients (17.1%) changing risk stratification group.
Thus, an urgent need exists for the identification of molecular signatures of melanoma progression which can be used to develop accurate prognostic markers and effective targeted therapies.
Genomic studies have been used to develop both prognostic biomarkers and to identify biomarkers to predict response to therapy.
In the original cohort used to develop the prognostic score, 56% of children admitted to hospital were positive for malaria.
Separate populations were used to develop the prognostic model (derivation cohort) and then validate it (validation cohort).
Multivariable logistic regression analysis was used to develop a prognostic model to estimate the risk of dying within 60 days from aSAH based on clinical and neuro-imaging characteristics.
We suggest that BPR can also be used to develop a prognostic gene signature for IPF by training a model with samples of rapidly progressive IPF versus slowly progressive IPF.
