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It was subsequently used to develop in vitro fertilization techniques for humans.
When in vitro models are available that either have a high human predictive value or are physiologically similar to the human situation, experimental data can be used to develop in silico models that will eventually be able to predict the human in vivo bioavailability of nanoparticles from their in vitro translocation rate.
Reprogramming technologies can be used to develop in vitro models of genetic and sporadic disease cases and effectively stratify patients, based on (i) the neuronal subtype that exhibits a disease-associated phenotype and (ii) the pathway that leads to this phenotype in each case (Fig 3).
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Qualitative techniques are used to develop in-depth cases.
The qualitative interviews with patients will be analysed by interpretative phenomenological analysis, a framework that can be used to develop in-depth descriptions of patients' experiences.
While a considerable amount of information was collected on social and behavioural characteristics of the subjects, this could not be used to develop in-depth and informative accounts of the life trajectories of each man.
The new funds will be used to develop an in-image advertising network for brands, retailers and other product advertisers, says the company.
Whereas Angpt1 can be protective, Angpt2 can worsen outcomes in sepsis, observations that are being used to develop biomarkers in sepsis [ 18– 20].
Furthermore, the results of in vitro testing (e.g. IC50 values in enzyme or receptor assays) could be used to develop predictive in silico tools.
In the past decades, dynamical systems have been used to develop models in physics, biology, chemistry, engineering and epidemiology; see for instance [1, 2] and [3].
The graphical risk presentations can also be used to develop skills in communicating benefits and risks to patients and their relatives in the acute setting.
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