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We used the pilot data estimates of variance to calculate the sample size required to obtain sufficient power (80% or 90%) for various differences in means (m1-m0).
Next, we used the pilot data set to build an LS-SVM to predict disease stage and an LS-SVM to predict the response to platin-based chemotherapy (MATLAB scripts were downloaded from LS-SVMlab version 1.5 [ 7, 8]).
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A multinomial choice model was estimated using the pilot data to confirm the face validity of the survey instrument.
Using the pilot data to calculate standardised effects sizes, the equivalence margin includes small differences (<0.37) but excludes moderate or large treatment differences.
Respondents to the pilot sample a mix of provider types, state of origin and experience level in providing CA and 3 pph activities, which was helpful when using the pilot data to produce a final survey instrument.
The efforts of the E-ADNI were not only concentrated in neuroimaging but also in fluid biomarkers, using the pilot data to validate and standardize results from across six different centers [ 41].
In the current study we evaluate whether tumour characteristics in an independent set of 49 patients can be predicted using the pilot data set with principal component analysis or LS-SVMs.
Using the pilot data of a study investigating stress and health among working Jordanian women, Hattar-Pollara and Dawani [ 18] reported a Cronbach alpha of the Arabic translated version of 0.86.
To build an analysis method that requires no prior knowledge of which junctions are alternatively spliced and to identify an alternative method to evaluate our technology using the pilot data, we applied an additive model to produce M-scores for each junction in each tissue.
Using the pilot data estimates of SD and correlation and assuming that each co-primary outcome will be tested at the 0.025 two-sided significance level, power calculations for analysis of covariance on the PSWQ-A outcome indicated the need for a total of 80 participants per group to attain 90% power, 70 participants per group to provide 85% power, and 60 participants per group to attain 78% power.
The procedures use the pilot sample data to estimate an "optimal" group size and then proceed to determine the number of groups by a stopping rule.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com