We could have used the continuous climatic suitability value of the pines distribution in the nuthatch models, but it would not have been possible to disentangle the current observed pine range from potential range closer to the fundamental distribution.
To make use of the continuous values of structural sensitivity and weighted entropy for each nucleotide site, we calculated the Pearson correlation coefficient between structural sensitivity and weighted entropy of the 4-fold degenerate sites in each gene.
In this case, we used these continuous values for one of the population clusters as the response variable, and a set of spatial variables that included climate, moisture, and elevation (Table 1) were used as predictors.
Conversely, we claim that traditional use of discretization, where the continuous values are replaced with discretized ones, can be detrimental if important information is lost by removing the original continuous values.
Does the classic use of discretization of removing the continuous values help improve performance?
Secondary analyses were performed for the top SNPs identified in the stage II cohort, using the continuous phenotype of CK-MB values and a dichotomised extreme CK-MB phenotype, which included participants within the first and fourth quartiles of the CK-MB distribution.
We use the continuous clinical CORE-OM score, with values between 0 and 40 (25).
Italic figures refer to ORs and 95% CI obtained using the continuous variable without categorization c P value.
For the clinical parameters, t-tests will be used for continuous values or the Mann-Whitney U-test when the variables are not normally distributed.
We note that the POBN method can be used with continuous values directly, however the continuous scoring algorithms that are currently available are computationally impractical for networks involving more than a few hidden nodes.
