Zygosity classification was initially based on questionnaire data using discriminant analyses.
The study used on-site questionnaires to collect data in six public park playgrounds in the U.S. and Denmark, to reveal cultural similarities and differences.
The derived equations will be used along with questionnaire data on historical exposure and exposure information from two previous studies 13, 14 to estimate current and retrospective exposure in the follow-up study.
Any ICD-10 or ICD-9 codes for cardiovascular or cerebrovascular disease recorded between 1981 and 2007 were extracted and used together with questionnaire data on vascular disease and electrocardiogram findings (as well as review of clinical notes when required) to define MI, angina, stroke, and TIA, as detailed previously (16, 18).
In IFS2 we had biomarkers of alcohol consumption that showed the same pattern of associations with BNP and other outcomes as seen using the questionnaire data on alcohol.
Although our sample size is too small to generate an in-depth, multivariate exploration of the effects of subject- and visit-specific characteristics on cytokine response, we were able to use the questionnaire data collected on health and lifestyle in a hypothesis-generating, exploratory analysis of the effects of these characteristics on TNF-α release.
Only these numbers were used on the questionnaires, for data entry, and in the subsequent analysis instead of names.
To preserve confidentiality, all patients will be allocated a unique study identifier, which will be used on all data collection forms and questionnaires; names or addresses will not appear on completed questionnaires or case report forms.
Lifetime cumulative number of menstrual cycles was computed using questionnaire data on ages at menarche and menopause, number of pregnancies, breastfeeding, oral contraceptive use (OC) and regularity pattern.
To preserve confidentiality, all patients will be allocated a unique study identification number, which will be used on all data collection forms and questionnaires.
