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Lead is not only the most abundant of heavy metals occurring in nature, it was also one of the first metals used on a large scale by man.
Valium was, significantly, one of the first psychoactive drugs to be used on a large scale on people who were basically fine.
Permanent exclusions are not being used on a large scale to exclude pupils.
Transfer printing was used on a large scale for the first time at Battersea.
Pachauri said: "With CCS it is entirely possible for fossil fuels to continue to be used on a large scale".
In the US, arsenic was used on a large scale which only partially cleared the weeds but poisoned the ecosystem.
The long war against chemical weapons use The first world war was the first occasion on which chemical weapons were used on a large scale in war.
But all of these tactics, first used on a large scale by the Russians, are also available to others — and not just other authoritarians.
Extrusion is easily adapted to mass production; it is already used on a large scale to manufacture construction shapes such as window frames and pipes.
The code has been used on a large range of problems, including text classification [Joachims, 1999c][Joachims, 1998a], image recognition tasks, bioinformatics and medical applications.
After much consideration and many individual experiments, he evolved his later system, and then this system was used on a large scale to exterminate the insane.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com