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We show that 3 5 kb fragment size mate-pair libraries and a scoring scheme specifically designed for transgene insertion site discovery allowed us to successfully discover transgene insertion sites in two widely used mouse models of Amyotrophic Lateral Sclerosis (ALS).
This review focuses on currently used mouse models of NASH with particular emphasis on liver morphology.
To explore this question, the researchers used mouse models of leukemia, engineered by transplanting human leukemia cells under the skin of immunocompromised mice.
Indeed, the two most widely used mouse models of depression, the unpredictable chronic mild stress (UCMS), and the CSD produce decreases42,43 or increases8,9,11 in VTA DA neurons' activity, respectively.
We therefore used mouse models of intranasal RV infection and immunisation to determine the induction, magnitude and specificity of antibody responses.
Researchers would like to see additional experiments to assess the effects of copper on widely used mouse models of Alzheimer's.
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That, he says, suggests that the widely used mouse model of cystic fibrosis "might not be appropriate".
By demonstrating that a widely used mouse model of autism does have gastrointestinal problems, and that these problems are associated with behavioral symptoms, the new research "shows us something fabulous," says Betty Diamond, an immunologist at the Feinstein Institute for Medical Research in Manhasset, New York.
In the present study, we used the genetically modified apolipoprotein E deficient (ApoE−/−) mouse, a widely used mouse model of atherosclerosis and natural hypercholesterolemia, to study the effect of dyslipidemia on endothelial VCAM-1 expression.
The data was generated using the DBA/2J strain, a widely used mouse model of glaucoma.
Using a widely used mouse model of polymicrobial sepsis, we analyzed the clinical efficacy of the newly developed SALP 19-2.5.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com