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Essentially, we can only say that the currently used methods do not allow for any conclusion on convergence.
However, the commonly used methods do not meet these criteria.
More sophisticated and much less commonly used methods do not include "the additivity assumption", i.e. nucleotides in different positions may depend on each other [ 14, 15].
Similar(57)
However, slip resistance coefficients determined using some methods do not correspond well to the perception of slipperiness by real users.
Recurrent mutations or homoplasy are unlikely to explain these results as excluding indel polymorphism and using robust methods do not qualitatively influence the results.
Most of the commonly used gap treatment methods do not distinguish between insertions and deletions.
These methods do not use all capabilities of the technology.
All the three methods do not use negative samples.
Unsupervised methods do not use any data to adjust internal parameters.
Moreover, the statistical methods do not use biological knowledge for prediction.
Since results obtained using this method do not use any approximations, they can provide benchmarks for performance comparison.
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