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The concentrations of the toxins and drugs used here were deduced from the literature.

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All measurements were deduced using photographic analysis.

Contacts between amino acids were deduced using molprobity.

The open reading frame (ORF) and the amino acid sequences were deduced using SeqMan (DNAstar).

Location of the mitochondrial genes were deduced, using online annotation server MITOS [ 14].

Amino acid sequences were deduced using ExPaSy (http://web.expasy.org/translate/.org/translate/

After 2006, capsular serogroups/serotypes were deduced using multiplex-PCR as described elsewhere [ 14, 15].

PCR and sequencing primers for BPS were deduced using the PyroMark® Assay Design 2.0 software (Qiagen).

The relative locations of these additional loci were deduced using BLAST analysis.

Amino acid sequences were deduced using the "translate" function of the program MEGA v.5.1 [ 31].

Backbone dihedral angles were deduced by using TALOS (Cornilescu et al, 1999).

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