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To identify the specific genes that are modulated by a specific biological process we used gene array analysis.
We used gene array analysis to determine change in global gene expression induced by K13 in human vascular endothelial cells (HUVECs).
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Analysis of data generated by gene array analysis, determination of intrahepatic cellular origin of transcript expression, and studies of intrahepatic gene expression using gene array analysis are also reviewed.
Here, we use gene array analysis as a platform to demonstrate general activation of the canonical arm of the Wnt pathway in human PDA.
We have previously demonstrated regulation of a host of implantation-related genes including LIF by PROK1 using gene array analysis (7).
Using gene array analysis, we found that mir-125a-5p mir-125a-5p mir-125a-5pexpression wasle mir-34b-3p expression was 7.69 times higher in OECs compared with YECs.
We had earlier identified a 67-gene signature associated with the presence of DTCs in the BM of breast cancer patients using gene array analysis (Supplemental Table 1) [ 12].
Since HSP90 inhibition leads to global depletion of oncogenic proteins involved in multiple pathways we applied global analysis using gene array technology to study new genes and pathways involved in the drug response in breast cancer.
Parsing data requires a sophisticated trial design that includes laboratory work to characterize patient tumors using gene arrays, proteomics, and analysis of regulatory pathways, as well as complex statistical analysis of subsets of patient outcomes.
Using the same individuals used for gene array analysis (n = 8/group), our analysis indicated that the frequencies and absolute numbers of individual monocyte and DC subsets did not vary with aging (Fig. S1).
Differences in hybridization platforms used in gene array analysis experiments can lead to significant differences in hybridization results.
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