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To estimate the parameter values used for the effectiveness of facemasks, we used available data from studies on N95 respirators and surgical facemasks.
We based our analysis on the imputed outcomes data used for the effectiveness trial [ 12].
Due to heterogeneity across studies, only the percentage of ulcers healed was reported and used for the effectiveness estimate.
The averages of these five estimates were then integrated into a single data set that was used for the effectiveness analyses.
LOCF was the primary analysis used for the effectiveness research sample (IAQ, CGI-I, CGI-S), whereas observed cases (OC) was the primary analysis used for the outcomes research sample (ASEX).
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An overview is primarily given of the methodological requirements currently used for the relative effectiveness assessment by NICE in England and the early benefit assessment by G-BA/IQWiG in German.
The following secondary outcome measures are specifically used for the cost effectiveness study.
Economic parameters and the detailed model structure used for the cost effectiveness analysis have been previously described.
The sensitivity estimates used for the cost-effectiveness model are somewhat lower than these figures, since the cost-effectiveness model assumes that some smear-negative TB cases are also culture-negative.
In this section we elaborate on the individual-based dynamic model and the data used for the cost-effectiveness analysis.
The values used for the cost-effectiveness calculations, including the demography and epidemiology of cholera in Bangladesh, are provided in Table 1.
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