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Parameters used for network generation are provided as Table S5 in Additional file 1.
Moreover, the interaction databases used for network generation might influence the result.
Molecules that are known to have direct and indirect associations were used for network generation.
The so-called focus genes were used for network generation and biological function and/or diseases analyses.
Specified lists of genes identified by RankProd as being affected by EGF were used for network generation and pathway analyses implemented in IPA tools.
The published gametocyte time course we used for network generation [ 30] omits the first 24 hours of sexual development as well as the commitment stage in the previous asexual cycle.
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In the first set of experiments the model used for network inference was that used for data generation.
The mismatch between the real mechanisms used for data generation and the models used for network inference may lead to arbitrary network structures.
These differential and unique protein sequences identified by PMF and MS/MS studies were subjected to BLAST analyses at TAIR database (The Arabidopsis Information Resource) and their homologous genes (bearing TAIR gene IDs, Additional file 1) used as inputs for network generation.
Ingenuity pathway analysis (IPA - Ingenuity® Systems, http://www.ingenuity.com) was used for biological network generation and functional analysis.
The working hypothesis for network generation is that the biological function involves locally dense interactions; thus, IPA uses an algorithm to attempt to generate networks that are as densely connected as possible [ 26].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com