LOO-CV is carried out in such a way that every object is removed once for validation, whereas the remaining data objects are used for model building.
The performance of a binary classifier is assessed using a test set ( S_{test} ) that consists of both positive (( S_{test}^ )) and negative (( S_{test}^ )) samples not used for model building [25].
Chance constrained fuzzy simulation based approach is one such methodology that merges the facets of chance constrained programming and fuzzy logic and is adopted here to carry out an analysis in determining optimal performance of a semi-batch epoxy polymerization reactor under uncertainty in kinetic parameters used for model building.
Forty stage I ovarian cancer and 40 control samples were used for model building.
This procedure was repeated four times with different subjects used each time, with 9 analytes (Table 4) used for model building.
COOT was used for model building.
These sequences defined the initial training set used for model building.
A manual forward stepwise approach was then used for model building.
Ten-fold cross-validation was used to evaluate the predictive accuracy of the prognostic model on a data set independent of the one used for model building.
All statistical analyses were performed using R version 2.6.1 (R Development Core Team, 2007), and the glmmML package [ 27] was used for model building.
A number of statistical methods such as partial least square (PLS), multiple regression, and principle component regression can be used for model building.
