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Separate groups of animals were used for each endpoint.
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MRI could also be used for pharmacological endpoint evaluation using concurrently administered MR contrast agents as surrogate indicators of therapeutic drug concentrations.
The last observation carried forward method (LOCF) for substitution of missing data was used for an endpoint analysis in the primary and all secondary outcome measures.
The results from this multicentre international FDG sub-study confirm that this has a large impact on data with FDG scans used for primary endpoint.
This study created an independent model in which the standard platelet count used for the endpoint was set at 30 × 10/L, with states including hemorrhage and adverse events.
The minimized signatures were built at probe level by using MFS for each endpoint.
Data from the last 9 months of each treatment arm will be used for endpoint analyses.
Continuous secondary efficacy endpoints were tested for significance using the same models as used for the primary endpoint.
An overall two-sided 5% significance level will be used for all superiority endpoint comparisons, and a one-sided 2.5% significance level will be used for all non-inferiority endpoints.
Proper training sets are used for fitting the endpoint and error models.
As a part of this contract, EQAPOL was required to operate under Good Clinical Laboratory Practices (GCLP) that are traditionally used for laboratories conducting endpoint assays for human clinical trials.
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CEO of Professional Science Editing for Scientists @ prosciediting.com