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These findings represent the first time that a polyaminated polyglutamate polymer is used for an efficacious and safe tumor delivery of RNAi following systemic administration.
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In situations where the RTS,S efficacy is low, the limited available resources may be better used for other efficacious interventions such as artemisinin-based combination therapies (ACTs), insecticide-treated mosquito net (ITN) and indoor residual spraying (IRS).
Equine F (ab') 2 fragments specific for H5N1 have been used for efficacious prophylaxis and therapy in a mouse model [8].
We suggest that TGZ may be used as an efficacious adjuvant chemotherapeutic agent for primary osteosarcoma.
A two-field gyrofluid model is used and an efficacious k-space SI operator for this problem is demonstrated.
In this form, HEV 239 has been used as an efficacious recombinant hepatitis E vaccine for human use [ 33].
In addition, we suggest the use of an efficacious platform for screening molecules as AD drugs using in vitro cell culture and in vivo AD fly and aggressive AD mouse model.
They are not effective when used for oral immunization but efficacious when administered by intranasal route.
The use of an efficacious treatment with artemisinin derivatives is one of the WHO's most preferable recommendations for decreasing the impact of malaria in sub-Saharan Africa.
According to Mr. Denis, a lab manager at IMRA: "It's not true that the plants that are [traditionally] used for diabetes [are always] efficacious for diabetes; so we screen [more plants], or go for something else".
Like many of the medications used for chronic pain, gabapentin requires titration to achieve an efficacious dose so that the rate and severity of adverse effects are minimised.
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CEO of Professional Science Editing for Scientists @ prosciediting.com