Exact(9)
Additionally, we will describe the indications for PSA, medications used, efficacy of sedation, and adverse events related to sedation in this group of children.
We used efficacy estimates based on the latest available data for RotaTeq®.
Cahill et al. [ 20] also used efficacy estimates from laboratory investigation data [ 30].
Only two out of 40 studies used efficacy data from the target country in their analysis.
Most couple counselling research has used efficacy study designs and applied structured therapeutic approaches [ 62].
Moreover, all cost-effectiveness studies of rhAPC used efficacy data extracted from the PROWESS trial, which probably do not reflect real-life practice at bedside [ 15].
Similar(51)
According to published data and adaption of general recommendation, we calculated IPD effectiveness of both vaccines using efficacy data, adjusted to serotype distribution in Germany for all age groups.
An intention-to-treat analysis will be performed using efficacy measures.
We simulated the impact of a combined annual mass diethylcarbamazine/albendazole (DEC/ALB) regimen applied at 80% coverage (using efficacy estimates given by Michael et al. [ 22]).
In this trial, we planned to recruit participants with PDS only, because a narrow and specific population will be more appropriate in a trial using efficacy design.
Clinical benefit was narrowly defined using efficacy (PFS/OS) under the prior assumptions that 1) efficacy was the paramount aspect of clinical benefit and 2) the use of PFS instead of OS has been controversial among Canadian HTA experts.
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