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Particle size analysis of the lyophilized formulas showed that Tween 80 was an effective nanoparticles stabilizer in contrast to Pluronic F68 and PVA which failed to prevent nanoparticles flocculation when they were used at high concentration.
These polyclonal fluids are used at high concentration to insure that all VLP antigens, even those with dramatically altered epitopes, should be captured and detected similarly.
The inhibitors used are said to be "potent" but are used at high concentration (10 uM).
When used at high concentration, this natural mediator enhanced the bioremediation capacity of POXC determining a rate degradation of 50% of both parabens in 30 minutes.
This cannot be explained by an insufficient amount of insulin in our assays as it was used at high concentration (100 nM).
These data provide in vivo confirmation of one of the strengths of biodegradable PBAEs, a strong safety profile, even when used at high concentration.
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BCA, although selective for CSE, it also inhibits CBS when used at high concentrations.
For instance, KOH is used at high concentrations (1 M or higher) to reach high extractions of humic matter, at the price of obtaining highly saline humic products, even though this is a minor problem because commercial humic products are largely diluted when applied to crops.
Several studies in mice have indeed shown very limited activities of aminoglycosides, even when used at high concentrations [21], [22].
Here we have shown that a variety of pharmacological reagents at used at high concentrations can trigger homotypic LD fusion in both fibroblasts and adipocytes.
It should be pointed out that NH4Ac was used at high concentrations in the odorant assays, probably above the normal range encountered naturally.
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