When used as directed, the drug is not hazardous.
Metabolife has consistently maintained that its products are safe when used as directed.
Drug makers insist that PPA products are safe and effective when used as directed.
Bayer said in a statement that it still believed Trasylol was beneficial when used as directed.
In a statement, Metabolife said its products were "safe and effective" when used as directed.
"We stand by the fact that we believe our current products are safe and effective when used as directed".
It is usually harmless if used as directed, but it can be hazardous, especially to children, and particularly if overused.
When used as directed, herbicides are generally safe, not only for the operator but also for wildlife and livestock.
"All Fixodent products are safe to be used when used as directed," Michelle Vaeth, a company spokeswoman, says.
Xanodyne Pharmaceuticals and Qualitest/Vintage Pharmaceuticals, which market the drug, say the medication is safe and effective when used as directed.
Neutrogena's spokeswoman, Lisa Wallender, said that the company complied with F.D.A. regulations and that its products "are safe and effective when used as directed".
