Prior research has used approaches including syllable count, easy word list, and frequency count, all of which have significant limitations.
Some commonly used approaches include 'one-versus-the-rest', 'one-versus-one', DAGSVM, and binary tree.
Some of the most frequently used approaches include the Anderson-Darling test, the Cramér-von Mises criterion, and the Kolmogorov-Smirnov test, among others.
Commonly used approaches include sample splitting, cross-validation, and bootstrapping.
Commonly used approaches include amino acid analysis, immunological methods (radioimmunoassay [ 2– 4], ELISA [ 5– 8]), column chromatography [ 9], and capillary electrophoresis [ 10– 10].
Some examples of the most commonly used approaches include MEME [ 24], AlignACE [ 25], MDScan [ 26], and Weeder [ 27] (for a comprehensive review see [ 28]).
Many researchers have taken up the challenge, using approaches including mucoadhesive drug delivery, colon delivery, particulate drug delivery such as nanoparticles, microcapsules, liposomes, emulsions, micelles, and so on.
Novel classes of antiviral compounds or biomolecules targeting viral replication mechanism are under development, using approaches including high-throughput small-molecule screening platforms and structure-based designs.
The shortcomings of current therapeutic modalities are highlighted and a broad spectrum strategy using approaches including (a) gossypol; (b) epigallocatechin-3-gallate; (c) UMI-77 (d) triptolide and (e) selinexor that can be used to overcome cell death resistance is presented.
miRNAs and their targets have been discovered using approaches including cloning and sequencing sRNAs [10], [17], bioinformatic prediction from genomic sequences [18], and sequencing cleaved mRNAs by parallel analysis of RNA ends (PARE) [19].
