The hDPI database used a protein microarray-based strategy to build human protein-DNA interactome [ 20].
Here, we used a protein microarray-based approach to systematically survey the entire human TF family and found numerous purified TFs with methylated CpG (mCpG -dependent DNA-binding activities.
Recently, Hu et al. used a protein microarray-based strategy to systematically characterize the repertoire of proteins bound to 752 predicted DNA motifs from previously published studies; the palindrome TCTCGCGAGA was characterized among them.
We compared antibody responses to monkeypox virus infection and human smallpox vaccination by using a protein microarray covering 92 95% (166 192 proteins) of representative proteomes from monkeypox viral clades of Central and West Africa, including 92% coverage (250 proteins) of the vaccinia virus proteome as a reference orthopox vaccine.
A protocol for high-throughput affinity determinations using a protein microarray and fluorescently labeled synthetic peptides was published by Kaushansky et al. [ 46].
Transcriptionally active PCR products (TAP products) corresponding to 1,988 C. burnetii open reading frames (ORFs) were tested using a protein microarray [ 66].
Here, we demonstrate a high-throughput methodology allowing rapid identification of the proteins binding to a given human RNA molecule using a protein microarray containing ~9,400 human recombinant proteins spotted in duplicate.
The aim of the present study was to use a protein microarray system for high throughput analysis (Bruix et al., 2005) to screen for autoantibody-based serum markers for early HCC, and to evaluate the value and timing of those autoantibodies in the early diagnosis of HCC.
For example, interactions of SH2 domain-containing proteins with phosphotyrosine binding partners in ERBB receptors have been characterized using a protein microarray-based approach [ 58].
Here, we used a protein-binding microarray (PBM) to identify the binding motifs of OsSMF1, which is a basic leucine zipper transcription factor involved in the regulation of rice seed maturation.
