Using a genotyping microarray or grouping multiplex PCR, the most common HR types we detected were HPV types-16, 18, 51, 58, and 33, and the most common LR type was HPV-70.
We developed and used a hybrid genotyping microarray to generate a high-resolution genetic map that covers 79% of the sequenced genome of Nasonia vitripennis.
We have created a suite of tools for the Galaxy web server aimed at handling nucleotide and amino-acid polymorphisms discovered by full-genome sequencing of several individuals of the same species, or using a SNP genotyping microarray.
We used high-resolution genotyping microarray Affymetrix CytoScan 750 K Array (Affymetrix, Santa Clara, CA, USA) according to the manufacturer's instructions.
In 27 out of 31 patients, only one disease-associated allele was detected using the genotyping microarray, and in the remaining cases, no variant was detected by the chip (four out of 31 patients).
We used SNP genotyping microarrays and identified 33 genomic regions (67 SNPs) associated (at the p < 10−6 level) with the risk of sporadic, BRCA-mutation-negative breast cancer.
Data from 133 arSTGD patients were analysed using the ABCR400 genotyping microarray; 10 results were confirmed by direct sequencing.
Current genome-wide association studies (GWAS) use commercial genotyping microarrays that can assay over a million single nucleotide polymorphisms (SNPs).
We hypothesised that quantitative estimates of allele frequencies – especially the relative allele frequencies comparing groups like cases and controls – can be derived from pooled DNA using SNP genotyping microarrays, similar to the way that expression microarrays estimate quantitative frequencies for mRNA transcripts [ 17].
Several studies have been reported on the use of genotyping microarray for genetic diagnosis of retinal disease, such as Stargardt disease, 22 Leber congenital amaurosis, 23 Usher syndrome, 24 autosomal recessive RP 25 and adRP.
