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Some of the complexity of using transporter KO mice to study CP function is demonstrated by folate transport.
Auxin efflux carrier proteins were identified using Transporter Classification on the JGI IMG database.
Genes encoding transporters were annotated by BLASTP using transporter encoding genes retrieved from the Transport Classification database with a cut-off of Evalue1e-20.
Li et al. [ 9] developed a general approach combining homology-based and machine learning methods, using transporter sequence features learned from well-curated proteomes as guides, to predict major transporter families/subfamilies defined in the transporter classification database.
A biophysical CCM is the direct transport of inorganic carbon across multiple membranes using transporters and carbonic anhydrases.
The ducts are lined by epithelial cells (cholangiocytes) which actively modify bile by secreting or absorbing solutes and water using transporters, exchangers, channels, and receptors, and by processes such as endocytosis, exocytosis, and pinocytosis.
To detoxify against the citrinin, the yeast cells mainly used glutathione modification and pumped out the toxin using transporters.
To enter the cell, glucose uses transporters that allow facilitated diffusion (via concentration gradients) through the cytoplasmic membrane.
Plants take up Zn from the soil using transporters from the Zn-regulated transporters in the iron (Fe -regulated transporter-like protein (ZIP) gene Fe -regulated
Thus by using transporters and receptor mediated endocytosis genes, enzymes and activated prodrugs could be delivered to cancer cells and metastatic tissues [ 37].
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Justyna Jupowicz-Kozak
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