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Maybe the Laysan albatross has evolved a survival trait that we haven't but desperately could use — tolerance.
With repeated use, tolerance develops, so that a user needs to take larger doses, but the accompanying dependence is not strong enough to be termed a physical addiction.
With prolonged use, tolerance and tachyphylaxis can occur and the elimination half-life may increase, up to days.
In addition, with long-term use, tolerance and dependence is likely.
For example, while hypnotics are readily available and easy to administer, limited data exist on their efficacy and safety with chronic use, tolerance and dependence may occur with long-term use and many patients prefer non-medication approaches to insomnia.
In addition, PET may in principle be useful for a qualitative and quantitative assessment of adaptions to the central opoid receptors resulting from opioid and stimulant drug seeking behaviour, development of compulsive drug use, tolerance and withdrawal syndromes.
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The world here is diminished without your presence and we are doing our best to remember all you taught us without having to say a word, but by your example of using tolerance, humor, wisdom and a big heart to live every day to the fullest.
This can be achieved using tolerance analysis tools.
The following are the assumptions considered while using tolerance capability expert software.
We review currently used tolerance assays, and examine the many parameters that affect assay outcomes.
Selected or engineered microbes that thrive in the presence of toxic chemicals can be assessed using tolerance assays.
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CEO of Professional Science Editing for Scientists @ prosciediting.com